DEVELOPMENTAL BIOLOGY - BIOL 312 SPRING 2002
| Instructor: | Dr. Michael Temkin 124 Bewkes Hall, Office Telephone: 229-5871 Home Telephone: 386-3025 |
| Class Meetings: | Lecture - Monday, Wednesday and Friday 9:40-10:40AM Valentine 103 Laboratory - Wednesday 1:15-4:15 PM or TBA Bewkes 108 |
| Laboratory Access: | If you want to spend more time working in the laboratory, a key for Bewkes 108 is available in the Science Library for after hours access. |
| Textbook: | Kalthoff, K. 2001. Analysis of Development, 2nd Edition. McGraw-Hill, Boston, 790pp. Schoenwolf, G. C. 2001. Laboratory Studies of Vertebrate and Invertebrate Embryos, 8th Edition. Prentice Hall, Upper Saddle River, 360 pp. |
| Web Sites: | http://it.stlawu.edu/~mtem/home.htm and Blackboard Site |
OBJECTIVES:
REQUIRED ASSIGNMENTS AND THEIR POINTS VALUES:
| Exam I | 100 pts. | Feb. 21 |
| Exam II | 100 pts. | March 28 |
| Final Exam | 150 pts. | May 10 Saturday 8:30-11:30 AM |
| Quizzes 4@10 pts. | 40 pts. | Jan. 31, Feb. 14, Mar. 7 and Apr. 18 |
| Lab Practical Exams: Quiz Midterm Final |
0000000 10 pts. 65 pts. 75 pts. |
00000000 Feb. 19 in Lecture March 12 in Lecture April 30 in Lecture |
| Lab Notebook | 50 pts. | Will be graded 3 times during the semester |
| Study Questions and Projects | 50 pts. | |
| Participation | 50 pts. | |
| TOTAL | 690 PTS. | (of which 250 pts. or 36% is associated with the lab) |
GRADES: Point Percentage
| 4 | Excellent |
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| 3.5 | Between Excellent and Good |
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| 3 | Good |
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| 2.5 | Between Good and Satisfactory |
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| 2 | Satisfactory |
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| 1.5 | Between Satisfactory and Lowest Passing Grade |
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| 1 | Passing Grade |
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| 0 | Failing Grade |
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EXAMS and QUIZZES:
Exams and quizzes will include the following: definitions, compare and contrast, diagram and label, diagram and describe, other types of short answer questions and essay questions. Some questions will require you to have not only memorized the material that we have studied, but understand it well enough so that you can apply the information to an unknown problem situation. Exam I, Exam II, and 100 pts of the Final Exam will cover the material presented in the first, second and third portions of the course, respectively. Fifty points of the Final Exam will be cumulative and require information that you learned throughout the course.
Practical exams and quizzes will require you to answer questions while viewing projected images of whole mounts or sections. Questions will require you to identify stages, structures, cell types, tissue types, cell and tissue fates, etc.
Make-up Exams and quizzes: Those who miss an exam or quiz and have a valid excuse will receive either a written or oral make-up.
LECTURE AND LABORATORY ATTENDANCE:
You are expected to be in lecture on Monday, Wednesday, and Friday from 9:40 until 10:40 AM. You need to accomplish lab assignment each week. I will be available in the laboratory on Wednesdays from 1:15 until 4:15 PM and by appointment. There are valid reasons why you may miss lecture, but these do not include the following: 1) finishing a paper for another course, 2) studying for a test for another course, 3) staying up too late, and 4) having made a plane, train, or boat reservation for a trip. If you know you are going to miss a lecture check with me ahead of time. This does not mean you leave me a message on my voice mail the day you miss class.
COURSE STUDY TOPICS:
| Developmental Processes | Developmental Principles |
| Gametogenesis | Principle of Epigenesis |
| Fertilization | Principle of Cellular Continuity |
| Cleavage | Principle of Overlapping Mechanisms |
| Gastrulation | Principle of Cytoplasmic Localization |
| Organogenesis | Principle of Default Programs |
| Histogenesis | Principle of Induction |
| Sex Determination | Principle of Reciprocal Interactions |
| Organismic Growth and Oncogenes | Principle of Differential Gene Expression |
| Senescence | Principle of Genetic and Paragenetic Information |
| Principle of Cell Differentiation |
LABORATORY SCHEDULE:
The Week of:
Jan. 20 - The Microscope and Gonads, Gametes, and Meiosis
Jan. 27 - Gonads, Gametes, and Meiosis
Feb. 3 - Sea Urchin Fertilization and Early Cleavage
Feb. 10 - Animal Cleavage and Frog Embryology
Feb. 17 - Frog Embryology and Early Chicken
Feb. 24 - Chicken 0 - 24 hr.
Mar. 3 - Midterm - Up to 24 hr. Chicken
Mar. 10 - Chicken 33 hr.
Mar. 24 - Chicken 48 hr.
Mar. 31 - Chicken 72 - 96 hr.
Apr. 7 - 10 mm Pig
Apr. 14 - 10 mm Pig
Apr. 21 - 10 mm Pig
Apr. 28 - Final Practical - 33 hr. Chick - 10 mm Pig
Laboratory Notebook and Required Drawings:
During the semester you will be required to illustrate specific developmental stages that you observe in the laboratory. These drawings should be kept in a notebook that is separate from notebooks that you use for lecture notes. In some cases more than one required illustration may be satisfied by a single drawing. Drawing must be titled, completely labeled, and magnification indicated. Labels need to be neat and readable!!