Faculty Advisor to the Student Affiliates of the American Chemical Society (SLUSAACS), Fall 2004 - 2008.

Teaching Projects

• ACS Text Conferences
  What goes into making a decision to try a new chemistry curriculum? How do we implement it? Why change? We wanted more hands-on experience and fewer lectures. The ACS text offers a variety of activities designed to engage students and challenge them to draw conclusions from sometimes unexpected experimental data, reinforcing the grounding of chemistry in observable rather than transmitted knowledge. Dr. Marano and I presented on some of our experiences and observations after the first year at the 18th Biennial ChemEd Conference at the University of British Columbia in Vancouver. http://nobel.scas.bcit.ca/chemed2005/programs.htm
  
  
• Interdisciplinary Explorations of Teaching and Learning (Bryn Mawr College).
  Co-creator of a yearlong series for faculty and doctoral students from all disciplines, highlighted by campus visits from Catharine Stimpson,
  Mary Belenky and Blythe Clinchy, 2003-2004. (http://serendip.brynmawr.edu/local/scisoc/grad/ideaforum/#prospectus)
  
  
• Graduate Idea Forum. (Bryn Mawr College)
  Co-creator of a yearlong series for faculty and doctoral students from all disciplines to discuss semi-popular books of broad academic interest, 2003-2004. (http://serendip.brynmawr.edu/local/scisoc/grad/ideaforum/index0203.html)
  
  
• Center for Science and Society: Brown Bag Lunch Weekly Series.
  "The Culture of Science" 2002-2003, (http://serendip.brynmawr.edu/local/scisoc/brownbag0203/archivefall02.html).
  "What Counts? Measuring Ourselves and the World" 2003-2004, (http://serendip.brynmawr.edu/local/scisoc/brownbag/)
  
  

Research Involving SLU Undergraduates -

Research Fellows

Matthew Millard ’09, A Stopped-Flow Study of the Binding Kinetics of the Anti-Tumor Drug Nogalamycin with DNA. Senior Year Experience with Honors 2008-09, Stradling Student Research Award Summer 2008. Honors Thesis 2008-2009.

Brian Palmer ’10, Synthesis of a ruthenium dimer compound. Clark Gage Research Fellows Program, Summer 2008.

Kristin Berretta ’10, Chemical models of anti-cancer pharmaceuticals based on ruthenium compounds with organic side chains. St. Lawrence University Fellows Program, Summer 2008.

Research Grant Award: St. Lawrence University Large Grant Spring 2006. Funds to be used for students & mentor to study use of circular dichroism instrument and to travel to McGill University to determine binding mode of ruthenium complexes with DNA.

Summer Research, Heuer Foundation Fellows Program in the Chemical Sciences. Faculty Mentor responsibilities include attending the American Chemical Society National Meeting in March 2006 to co-present research results with Heuer Student Fellows(selected freshmen and sophomores)..
Faculty mentor for three undergraduate student research projects:

1) Stephanie Walter '09, DNA Synthesis and DNA Binding Properties of Diimine Complexes of Ruthenium with Ligands Featuring Aromatic Side Chains. Summer 2006. Honors Thesis, 2007-2008.

2) Jennifer Achtyl '08, Synthesis and DNA Binding Properties of Ruthenium 1,10-phenanthroline dipyrido phenazine based Dimer Complexes. Summer 2006. Honors Thesis, 2007-2008.

3) Ariel Riezenman '08, DNA Binding Studies of Two New Classes of Metal Complexes. Summer 2005.

Student Presentations: The presenter's name is underlined.

Achtyl, Jennifer & Glazier, S. Synthesis of a Ruthenium Polypyridyl Complex for Kinetics Studies. 233rd ACS National Meeting, Chicago, IL, March 2007.

Walter, Stephanie & Glazier, S. Synthesis of Ruthenium Complex with Bipyridine Ligands Featuring Aromatic Side Chains for Use in DNA Binding. 233rd ACS National Meeting, Chicago, IL, March 2007.

Kloek, Paul, Glazier, S., & Law, N. Exploring Metallacrowns: Do Metallacrowns of First Row Transition Elements Fluoresce? Presented by Paul Kloek at the SLU Festival of Science, April, 2006.

Riezenman, Ariel & Glazier, S. DNA Binding Studies of Ruthenium Polypyridyl Complexes and the Role of Sephadex. Presented by Ariel Riezenman at the 231st ACS National Meeting, Atlanta, GE, March 2006 and SLU Festival of Science, April 2006.

Chapp, Timothy, Law,N. & Glazier S. Design of Ruthenium Dimer Complexes for Intercalation with DNA. Presented by Timothy Chapp at the 229th ACS National Meeting, San Diego, CA, March 2005, and SLU Festival of Science, April 2005. SYE Thesis 2004-2005.

 

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Selected Publications/Presentations

Research Publications (names of research students supervised are indicated by *)

Millard, M.* and Glazier, S. Combined Isothermal Titration Calorimetry and Fluorescence Stopped Flow Study of the DNA Threading Mechanism of Nogalamycin. Journal of Physical Chemistry B, in preparation. 

Dalton, S., Glazier, S.., Leung, B., Win, S., Megatulski, C., Burgmayer, S.J.N. DNA Binding by Ru(II)-bis(bipyridine)-pteridinyl complexes. Journal of Biological Inorganic Chemistry, 13, 1133-1148, 2008

Glazier, S., Barron, J., Morales, N., Ruschak. A.M., Houston, P. L. & Abruña, H. D. Quenching Dynamics of the Photoluminescence of [Ru(bpy)3]+2 pendant PAMAM Dendrimers by Nitro Aromatics and Other Materials. Macromolecules 36, 1272-1278, 2003.

Barron, J., Glazier, S., Bernhard, S., Takada, K. & Abruña, H. D. Photophysics and Redox Behavior of Chiral Transition Metal Polymers. Inorg. Chem. 42, 1448-1455, 2003.

Glazier, S., Barron, J., Houston, P. L. & Abruña, H. D. Photophysics of PAMAM-Based Den-drimers of Polypryridyl Complexes of Ruthenium. J. Phys. Chem. B 106, 9993-10003, 2002.

Glazier, S. Photophysics of Ru Polypyridyl Dendrimers and Polymers of Deliberate Architecture. Doctoral dissertation, 2001.

Herrero, E., Glazier, S., Buller, L.J., & Abruña, H.D. X-ray and Electrochemical Studies of Cu UPD on Single Crystal Electrodes in the Presence of Bromide: Comparison Between Au(III) and Pt(III) Electrodes. J. Electroanal. Chem. 461, 121-130, 1999.

Herrero, E., Glazier, S., & Abruña, H.D. X-ray and Electrochemical Studies of Cu UPD on Au(III) Single Crystal Electrodes in the Presence of Bromide. J. Phys. Chem. B 102, 9825-9833, 1998.

Aegerter, P.A, Quigley, W.W.C., Simpson, G.J., Ziegler, D.D., Logan, J.W., McCrea, K.R., Glazier, S., & Bussell, M.E. Thiophene Hydrodesulfurization Over Alumina-Supported Molybdenum Carbide and Nitride Catalysts: Adsorption Sites, Catalytic Activities, and Nature of the Active Surface. J. Catalysis 164, 109-121, 1996.

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Research Presentations (names of research students supervised are indicated with *)

Glazier, S., Berretta, K*., Walter, S.* Chemical Models of DNA Binding Based on Ruthenium Compounds with Organic Side Chains.  Northeast Regional Meeting of the ACS, Burlington, VT, June 29 – July 2, 2008

Glazier, S., Dalton, S., Burgmayer, Sharon, J. Nieter. DNA Intercalation by Ru(II)-bis(bipyridine)-pteridinyl Complexes. 235th ACS National Meeting, New Orleans, LA, April 6 –10, 2008.

Glazier, S. & Achtyl, J.* Alternative Synthesis, Characterization, and DNA-binding of a [Ru(phen)2dppz]2+ Phenazine Linked Dimer. 234th ACS National Meeting, Boston, MA, August 19 –23, 2007.

Glazier, S., DNA Intercalation by Ru(II)-bis(bipyridine)-pteridinyl Complexes. Invited Talk at SUNY Potsdam, Potsdam NY, Feb 2006.

Glazier, S., Dalton, Shannon*, & Burgmayer, S.J. Effects of Hydrogen Bonding Ability in DNA Binding Using Ruthenium Pteridinyl-phenanthroline Complexes. 227th ACS National Meeting, Anaheim, CA, March 31, 2004.

Glazier, S., Barron, J., Díaz, D., Ho, W., Houston, P., & Abruña, H.D. Dimensionality Effects of Redox Active Dendrimers. Polymer Outreach Program, Cornell Center for Materials Research, Cornell University, May 22, 2000.

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Pedagogy Publications/Presentations - presenter's name is underlined.

Glazier, S., Eisen, L., and Marano, N. A Closer Look at Trends in Boiling Points of Hydrides: Using an Inquiry Based Approach to Teach Intermolecular Forces of Attraction. Journal of Chemical Education, in preparation.

Glazier, S. Roles of Intermolecular forces of attraction in boiling point trends, DNA structure and drug design. Workshop facilitator for 11 high school teachers, Rochester, NY August 2nd 2008.

Glazier, S., Law, N., & Dickson, E. Benefits of a Collective Approach to Independent Research. Oral Presentation at the 20th Biennial Conference on Chemical Education, Indiana University, IN July 27th – July 30th 2008.

Glazier, S., Eisen, L. & DeCunzo, P. ACS Advanced Chemistry.  Workshop facilitator for 17 high school teachers, Pittsburgh, PA July 6th – 11th 2008.

Glazier, S. & Bell, J. ACS Advanced Chemistry.  Workshop facilitator at National Science Teachers Association Conference on Science Education, Birmingham, AL December 6th – 7th 2007.

Glazier, S., Bloom, B. & Verdell, E. ACS Advanced Chemistry.  Workshop facilitator for 30 high school teachers, Houston, TX July14th – 19th 2007.

Glazier, S.  Engaging Students Using Current Topics in Chemical Research.  Oral Presentation at the 19th Biennial Conference on Chemical Education, Purdue University, IN July 30th – August 3rd 2006.

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