Faculty Advisor to the Student Affiliates of the American Chemical Society (SLUSAACS), Fall 2004 - present

Research Interests
Design, Synthesis and Characterization of Binding Mode to DNA by Ruthenium Polypyridyl Complexes.

Teaching Projects

• ACS Text Conference
  What goes into making a decision to try a new chemistry curriculum? How do we implement it? Why change? We wanted more hands-on experience and fewer lectures. The ACS text offers a variety of activities designed to engage students and challenge them to draw conclusions from sometimes unexpected experimental data, reinforcing the grounding of chemistry in observable rather than transmitted knowledge. Dr. Marano and I presented on some of our experiences and observations after the first year at the 18th Biennial ChemEd Conference at the University of British Columbia in Vancouver. http://nobel.scas.bcit.ca/chemed2005/programs.htm
  
  
• Interdisciplinary Explorations of Teaching and Learning (Bryn Mawr College).
  Co-creator of a yearlong series for faculty and doctoral students from all disciplines, highlighted by campus visits from Catharine Stimpson,
  Mary Belenky and Blythe Clinchy, 2003-2004. (http://serendip.brynmawr.edu/local/scisoc/grad/ideaforum/#prospectus)
  
  
• Graduate Idea Forum. (Bryn Mawr College)
  Co-creator of a yearlong series for faculty and doctoral students from all disciplines to discuss semi-popular books of broad academic interest, 2003-2004. (http://serendip.brynmawr.edu/local/scisoc/grad/ideaforum/index0203.html)
  
  
• Peer Lead Instruction: Training for Undergraduate Peer Leaders.
  Co-creator and trainer for a new supplemental program for freshman in chemistry, biology, physics and math to replace traditional problem sessions, August 21-22, 2003.
  
  
• Center for Science and Society: Brown Bag Lunch Weekly Series.
  "The Culture of Science" 2002-2003, (http://serendip.brynmawr.edu/local/scisoc/brownbag0203/archivefall02.html).
  "What Counts? Measuring Ourselves and the World" 2003-2004, (http://serendip.brynmawr.edu/local/scisoc/brownbag/)
  
  

Research Involving SLU Undergraduates - Students' names are underlined.

Research Grant Award: St. Lawrence University Large Grant Spring 2006. Funds to be used for use of circular dichroism instrument and travel to McGill University to determine binding mode of ruthenium complexes with DNA.

Summer Research, Heuer Foundation Fellows Program in the Chemical Sciences. Mentor responsibilities include attending the American Chemical Society National Meeting in March 2006 to co-present research results with Heuer Student Fellows.
Summer 2006: Faculty mentor for two undergraduate student research projects:
1) DNA Synthesis and DNA Binding Properties of Diimine Complexes of Ruthenium with Ligands Featuring Aromatic Side Chains, with Stephanie Walter '09
2) Synthesis and DNA Binding Properties of Ruthenium 1,10-phenanthroline dipyrido phenazine based Dimer Complexes with Jennifer Achtyl '08.
Summer 2005: Faculty mentor for one undergraduate student research project: DNA Binding Studies of Two New Classes of Metal Complexes with Ariel Riezenman '08.

Other Student Research:
Kloek, Paul, Glazier, S., & Law, N. Exploring Metallacrowns: Do Metallacrowns of First Row Transition Elements Fluoresce? Presented by Paul Kloek at the SLU Festival of Science, April, 2006.

Riezenman, Ariel & Glazier, S. DNA Binding Studies of Ruthenium Polypyridyl Complexes and the Role of Sephadex. Presented by Ariel Riezenman at the 231st ACS National Meeting, Atlanta, GE, March 2006.

Chapp, Timothy, Law, N., & Glazier, S. Characterization and DNA Intercalation of Ru(bpy)2)(dcbpy). Presented by Timothy Chapp at the SLU Festival of Science, April 2005.

Chapp, Timothy, Law, N. & Glazier S. Design of Ruthenium Dimer Complexes for Intercalation with DNA. Presented by Timothy Chapp at the 229th ACS National Meeting, San Diego, CA, March 2005.

Faculty mentor for SLU Senior Thesis: Undergraduate student thesis research project, Synthesis and DNA Binding of 'Ru(bpy)2dcbpyl]PF6 with Timothy Chapp '05.

Selected Publications/Presentations

Research Publications (names of research students supervised are indicated by underline)

Glazier, S., Dalton, S., Albano, A., Alaishuski, L., Burgmayer, Sharon J. Nieter, DNA Intercalation by Ru(II)-bis(bipyridine)-pteridinyl Complexes. Biological Inorganic Chemistry 2006, In preparation.

Glazier, S., Barron, J., Morales, N.*, Ruschak. A.M., Houston, P. L. & Abruña, H. D. Quenching Dynamics of the Photoluminescence of [Ru(bpy)3]+2 pendant PAMAM Dendrimers by Nitro Aromatics and Other Materials. Macromolecules 36, 1272-1278, 2003.

Barron, J., Glazier, S., Bernhard, S., Takada, K. & Abruña, H. D. Photophysics and Redox Behavior of Chiral Transition Metal Polymers. Inorg. Chem. 42, 1448-1455, 2003.

Glazier, S., Barron, J., Houston, P. L. & Abruña, H. D. Photophysics of PAMAM-Based Dendrimers of Polypryridyl Complexes of Ruthenium. J. Phys. Chem. B 106, 9993-10003, 2002.

Glazier, S. Photophysics of Ru Polypyridyl Dendrimers and Polymers of Deliberate Architecture. Doctoral dissertation, 2001.

Herrero, E., Glazier, S., Buller, L.J., & Abruña, H.D. X-ray and Electrochemical Studies of Cu UPD on Single Crystal Electrodes in the Presence of Bromide: Comparison Between Au(III) and Pt(III) Electrodes. J. Electroanal. Chem. 461, 121-130, 1999.

Herrero, E., Glazier, S., & Abruña, H.D. X-ray and Electrochemical Studies of Cu UPD on Au(III) Single Crystal Electrodes in the Presence of Bromide. J. Phys. Chem. B 102, 9825-9833, 1998.

Aegerter, P.A, Quigley, W.W.C., Simpson, G.J., Ziegler, D.D., Logan, J.W., McCrea, K.R., Glazier, S., & Bussell, M.E. Thiophene Hydrodesulfurization Over Alumina-Supported Molybdenum Carbide and Nitride Catalysts: Adsorption Sites, Catalytic Activities, and Nature of the Active Surface. J. Catalysis 164, 109-121, 1996.

Poster Presentations (names of research students supervised are underlined)

Glazier, S., Engaging Students Using Current Topics in Chemical Research and Using CHEMISTRY, the ACS General Chemistry Text, 19th Biennial Conference on Chemical Education, West Lafayetter, IN, to be presented July 30 - August 3, 2006.

Glazier, S., DNA Intercalation by Ru(II)-bis(bipyridine)-pteridinyl Complexes. Invited Talk at SUNY Potsdam, Potsdam NY, Feb 2006.

Burgmayer, S.J., Dalton, S., Glazier, S., Alaishuski, L., & Megatulski, C. Investigation of DNA Binding and Intercalation by Ruthenium Pteridinyl-Phenanthroline Complexes, International Conference on Bioinorganic Chemistry, presented by S.J. Burgmayer, Ann Arbor, MI, August, 2005.

Chapp, Timothy, Law, Neil & Glazier, S. Synthesis, Characterization and DNA Intercalation of Ru(bpy)2(dcbpy), presented by T. Chapp, Festival of Science, Canton, NY, April, 2005.

Chapp, Timothy, Law, Neil & Glazier, S. Design of Ruthenium Dimer Complexes for Intercalation with DNA, presented by T. Chapp, 229th ACS National Meeting, San Diego, CA, March, 2005.


Glazier, S., Dalton, Shannon, & Burgmayer, S.J. Effects of Hydrogen Bonding Ability in DNA Binding Using Ruthenium Pteridinyl-phenanthroline Complexes. 227th ACS National Meeting, Anaheim, CA, March 31, 2004.

Dalton, Shannon, Glazier, S., & Burgmayer, S.J. Possible Intercalation of DNA by Ruthenium(II) Pteridinyl Complexes. 5th annual Drexel Graduate Poster Session, Philadelphia PA, January 15, 2004.

Burgmayer, S.J., Alaishuski, L., Glazier, S., & Megatulski, C. Investigation of DNA Binding and Intercalation by Ruthenium Pteridinyl-phenanthroline Complexes. Gordon Conference Metals and Biology presented by S.J. Burgmayer, Ventura, CA, February 2, 2003.

Glazier, S., Barron, J., Díaz, D., Ho, W., Houston, P., & Abruña, H.D. Dimensionality Effects of Redox Active Dendrimers. Polymer Outreach Program, Cornell Center for Materials Research, Cornell University, May 22, 2000.

Glazier, S., Chen, X., Grochala, W., Abruña, H.D., Hoffman, R., & Ho, W. Transient Optical Properties of Molecular Materials. NSF site visit, Cornell Center for Materials Research, Cornell University, July 12, 1999.

Glazier, S., Barron, J., Merschrod, E., Reimhult, E., Hodson, E., Jenkins, D., Yang, L., Abruña, H.D., Ho, W., Houston, P., & Tang, C. Chemical Control at the Spatial and Temporal Limits. NSF site visit, Cornell Center for Materials Research, Cornell University, October 6, 1998.

Glazier, S., Aegerter, P.A, Logan, J.W., McCrea, K.R., & Bussell, M.E. Thiophene Hydrodesulfurization Over Alumina-Supported Molybdenum Carbide and Nitride Catalysts. NCUR-10, University of North Carolina, April 18-20, 1996.


Return to the Faculty/Staff Page